CURRENT POSITIONS

Research Technician - Neurosciences / Req # 005 2022
Posted 20 days ago
Post Date: September 16, 2022   Author: Human Resources
Job Type: Full Time
Location: 686 Fair Oaks Ave. Pasadena, CA 91105

SUMMARY:

Huntington Medical Research Institutes is an independent, nonprofit organization dedicated to improving lives through patient-focused scientific research. Our brand-new state of the art laboratory anchors the biomedical corridor on South Fair Oaks in Pasadena. Our scientists' research focuses on the connection between the brain and heart, developing diagnostic tools to help treat common diseases of these vital organs that affect every family.

  • Participate in the HMRI Aging Study through preparation of biological samples and running established methods for biochemical analysis to identify molecules utilizing methods including liquid chromatography, gas chromatography, ion chromatography, mass spectrometry, high-performance thin layer chromatography, MSD multiplex chemiluminescence assays for biomarker discovery in urine, CSF and plasma from Alzheimer’s disease (AD) patients.
  • Bench chemistry and analysis for the characterization and quantification of brain aging biomarkers.
  • The Research Technician will support the neurosciences department organizational systems for maintenance and optimization of the laboratory, inventory, clinical sample retention and databases.  
  • Record and store data that comes from any analyses done on the instruments
  • Analyze data and report results, with the aim of contributing to the preparation of manuscripts for publication.
  • The Research Technician also performs a wide range of job duties as assigned and requested.

JOB QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed below are representative of the knowledge, skill, and/or ability required. 

  • Carries out technical aspects of scientific studies.
  • May be involved with analysis of data, presentations, writing, lab management, etc.
  • The Research Technician also performs a wide range of job duties as assigned and requested.

 Education and Experience

  • A Bachelor’s degree in a scientific discipline with two years’ experience or MS degree with one year of experience or an equivalent combination of related education and experience.
  • Outstanding computer skills. Must be proficient with MS Office programs (Word, Excel, Outlook).
  • Experience in liquid chromatography and mass spectrometry.
  • Excellent written and oral communication skills.
  • Excellent bench chemistry skills.
  • Accurately maintain lab notebooks.
  • Keep records of lab inventories.
  • Sound judgement and decision-making capability.
  • Observes laboratory safety and security procedures.
  • Uses laboratory equipment and materials properly.
  • Must be reliable and conscientious self-starter with excellent attention to detail and the ability to coordinate multiple projects and deadlines.
  • Ability to build and maintain strong relationships with colleagues, building respect, consensus, and trust across reporting lines.

Follow instructions from supervisors and HMRI leadership

Postdoctoral Fellow, Cardiovascular Research Laboratory
Posted 36 days ago
Post Date: August 31, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

Postdoctoral positions are available in July 2022 in the Cardiovascular Research Laboratory at Huntington Medical Research Institutes (HMRI), Pasadena, CA to investigate a novel Ser/Thr phosphatase in the heart and brain with age and following injury.  In addition, the project will define the epigenetic mechanisms required for phosphatase mediated regulation of transcriptional changes that is important for cardiac homeostasis in young and aging mice. Using both in vitro and in vivo model systems we will determine novel targets that regulate protein expression  and metabolic signaling with aging. Candidates with a background in cell and myocardial biology will be preferred. Experience in molecular and cell biology techniques, biochemistry, bioinformatics, and cardiac mouse models are all considered strengths for this position.

Candidates, with a recent PhD degree, and a good track record of publications, will be given priority. The initial appointment will be for two years with the possibility of extension. Salary will be commensurate with qualifications, laboratory experience, and institutional guidelines. 

TO APPLY: Please send application materials (CV, a brief summary of career goals and objectives) and a list of three professional references to careers@hmri.org. No phone calls, please. Private letters of recommendation can be submitted using this form: http://bit.ly/postdocletter

Nicole Purcell, PhD
Associate Professor HMRI
Cardiovascular Research Program
Scientific Director of Education
Huntington Medical Research Institutes (HMRI) 

EEO POLICY: HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Director of Major Gifts
Posted 62 days ago
Post Date: August 5, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

The Director of Major Gifts is an essential part of HMRI, providing leadership in the fundraising activities of the organization. HMRI seeks a dynamic individual who will be responsible for major gifts fundraising activities, ensuring that donor cultivation, solicitation, and stewardship activities are consistent with the organization’s mission and strategic plan. The primary responsibility is to engage key stakeholders in activities that increase philanthropic revenue and support to the organization. Under the supervision of the Chief Development Officer, the Director of Major Gifts is responsible for expanding and diversifying the donor base. The successful candidate will help cultivate and solicit new relationships to build HMRI’s philanthropic revenue streams; develop a revenue growth plan that builds out a robust major gifts program; engages current and prospective major donors; and is responsible for identifying and researching funding opportunities; writing and submitting gift proposals; and executes successful donor stewardship.

QUALIFICATIONS REQUIRED:

 To perform this job successfully, an individual must be able to perform each essential duty satisfactorily and maintain a high level of integrity and confidentiality. The requirements listed below are representative of the knowledge, skill, and/or ability required.

  • A bachelor’s degree from an accredited four-year college or university;
  • Experienced philanthropy professional with a minimum of 5 years demonstrated successful fundraising, particularly in major gifts preferably in a medical or academic environment;
  • Knowledge of fundraising principles and techniques;
  • Previous experience using Blackbaud Raiser’s Edge software or another donor database;
  • Ability to build and maintain strong relationships with colleagues and prospects, building respect, consensus, and trust across reporting lines;
  • Knowledge of the Southern California philanthropic community and donors to scientific research a plus;
  • Build and maintain positive relationships with key stakeholders;
  • Proven track record of developing and closing new charitable contributions, and maintaining long-term major gift donors, meeting, and exceeding revenue goals and fundraising metrics;
  • Strong verbal and written presentation skills, including the ability to tell compelling stories and deliver persuasive presentations; and
  • The Director of Major Gifts also performs other duties as assigned.

 

  • SUPERVISORY RESPONSIBILITIES: None

    PHYSICAL DEMANDS:

    The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

    While performing the duties of this job, the employee is regularly required to sit and speak or listen.  The employee frequently is required to use hands, fingers, and arms to operate personal computers, telephones, and other business-related equipment.  The employee is occasionally required to stand and walk. Employee may be expected to drive to other locations/offsite meetings/events.

    EEO POLICY:

    HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

     

    VERIFICATION:  All higher education, academic degrees, and employment will be verified.

    Education and Experience

    • Bachelor’s degree required.
    • Minimum of five years of development/fundraising and non-profit experience required.
    • Performs philanthropy activities with discretion, integrity and confidentially.
    • Comfortable working in a scientific research and educational environment.
    • Knowledge of experience working with Blackbaud Raiser’s Edge NXT or another donor database.
    • Outstanding computer skills, proficient with MS Office programs (Word, Excel, Outlook).
    • Excellent written, oral, and interpersonal communication skills.
    • Good judgment and decision-making ability.
    • Takes initiative, is a resourceful, reliable, and conscientious self-starter with excellent attention to detail and ability to coordinate multiple projects and deadlines.
    • Anticipates needs before others ask.
    • Ability to build and maintain strong relationships with colleagues, building respect, consensus, and trust across reporting lines.
    • Comfortable working in an in-person office environment and wearing masks as appropriate.
    • Thrives in a collaborative team environment and has a collegial spirit in sharing ideas and receiving constructive feedback.
Research Technician, Cardiovascular Signaling Research
Posted 64 days ago
Post Date: August 3, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

 

DEPT: Cardiovascular Signaling

SALARY LEVEL: $18-22 per hour (commensurate with experience) 

SUMMARY:

Huntington Medical Research Institutes is an independent, nonprofit organization dedicated to improving lives through patient-focused scientific research. Our brand-new state of the art laboratory anchors the biomedical corridor on South Fair Oaks in Pasadena. Our scientists' research focuses on the connection between the brain and heart, developing diagnostic tools to help treat common diseases of these vital organs that affect every family.

The Research Technician's primary purpose is to assist the Associate Professor in setting up new lab at HMRI. The Research Assistant must be comfortable with rodent models and isolate primary cardiomyocytes and astrocytes for ongoing research in the laboratory, will maintain primary cell culture, will work with the PI and other lab members on experiments and upkeep of laboratory. Some in-house training will be offered for the specific methods and equipment.

The Research Technician reports directly to the Associate Professor and interfaces with other HMRI staff members from the cardiovascular department (research scientists, technicians, and laboratory supervisors). 

JOB QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed below are representative of the knowledge, skill, and/or ability required.

  • Assist in preparation of primary cardiomyocytes, astrocytes, and neonatal rat heart cells
  • Maintain animal colony genotyping and record keeping as well as maintaining several lines of cultured cells, prepare chemical solutions, and assist PI and other lab members with experiments
  • Perform laboratory and tissue culture facility maintenance duties (including ordering supplies, assuring that lab equipment is kept in working condition and general clean up)
  • Interact easily with faculty, postdoctoral scholars, students, and other research staff in a medium sized laboratory
  • May be involved with analysis of data, presentations, writing, etc.
  • The Research Technician also performs a wide range of job duties as assigned and requested.

Education and Experience

  • Bachelor’s degree in a scientific discipline with 2+years of laboratory experience
  • Theoretical knowledge of biological science, chemistry, biochemistry or molecular biology or equivalent combination of education, training, and experience
  • Experience handling mice, breeding management
  • Knowledge of basic laboratory procedures and equipment, including preparation of buffers
  • Knowledge of tissue culture and experience with maintenance of tissue culture facility
  • Ability to follow basic research protocols and follow instructions closely
  • Attention to protocols and details.
  • Ability to work independently and cooperatively.
  • Ability to communicate with colleagues and superiors, including asking questions and notification of problems
  • Experience with preparing primary cultures, maintaining cell lines, and preparing chemical solutions.
  • Outstanding computer skills. Must be proficient with MS Office programs (Word, Excel, Outlook).

PHYSICAL DEMANDS:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and speak or listen.  The employee frequently is required to use hands, fingers, and arms to operate personal computers, telephones, other business-related equipment, and work near moving mechanical parts.  The employee is occasionally required to stand and walk. The employee is occasionally exposed to airborne particles or toxic chemicals, bloodborne and airborne pathogens or infectious materials.

While performing the duties of this job, the noise level in the work environment is usually quiet to moderate.

The employee must occasionally lift and/or move more than 30 pounds.

Specific vision abilities required by this job include Close vision; Distance vision; Color vision; Peripheral vision; Depth perception and ability to adjust focus.

The above statements are intended to describe the general nature and level of work required of this position.  They are not intended to be construed as an exhaustive list of all responsibilities and skills required of personnel so classified.

APPLICATION: Please send application materials (cover letter, resume/CV) and a list of three professional references to careers@hmri.org. No phone calls, please.

 

EEO POLICY:

HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Postdoctoral Fellow - Neuroscience Department
Posted 64 days ago
Post Date: August 3, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

Huntington Medical Research Institutes is an independent, nonprofit organization dedicated to improving lives through patient-focused scientific research. Our brand-new state of the art laboratory anchors the biomedical corridor on South Fair Oaks in Pasadena. Our scientists' research focuses on the connection between the brain and heart, developing diagnostic tools to help treat common diseases of these vital organs that affect every family.

A postdoctoral position is available immediately in the Neuroscience Department at Huntington Medical Research Institutes (HMRI), Pasadena, California, to discover non-invasive biomarkers of Alzheimer’s Disease and investigate mechanisms that increase the risk of dementia in an elderly cohort. The project will examine molecular profiles in biofluids and biochemical/bioenergetic mechanisms of oxidized and signaling lipids that differentiate cognitively healthy individuals from those who are at risk of developing Alzheimer’s disease. The overall objective is to discover novel diagnostic biomarkers of Alzheimer’s disease and develop new tests for wider screening of an aging population.  

We welcome applications from highly motivated and independent-minded individuals. The initial appointment will be for two years with the possibility of extension. Salary will be commensurate with qualifications, laboratory experience, and institutional guidelines.

 

JOB QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed below are representative of the knowledge, skill, and/or ability required. 

  • PhD degree in Chemistry/Biochemistry, with expertise in analytical instrumentations and simple chemical synthesis/modification of oxidized lipid metabolites.
  • Candidates with a good track record of publications, and experience in mass spectrometry, lipidomics, proteomics, click chemistry, development of colorimetric or fluorescence assay.
  • Experience in small molecule quantification and detection methods will be an advantage.
  • Excellent written and oral communication skills and an ability and interest in mentoring students
  • Good judgment and decision-making capability
  • Observes laboratory safety and security procedures
  • Uses laboratory equipment and materials properly
  • Must be a reliable and conscientious self-starter, with excellent attention to detail and ability

to coordinate multiple projects and deadlines

  • Ability to build and maintain strong relationships with colleagues, building respect, consensus, and trust across reporting lines

 

SUPERVISORY RESPONSIBILITIES:

None.

 

PHYSICAL DEMANDS:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

 

While performing the duties of this job, the employee is regularly required to sit and speak or listen.  The employee frequently is required to use hands, fingers, and arms to operate personal computers, telephones, other business-related equipment, and work near moving mechanical parts.  The employee is occasionally required to stand and walk.

 

While performing the duties of this job, the noise level in the work environment is usually quiet.

 

The employee must occasionally lift and/or move more than 10 pounds.

 

The above statements are intended to describe the general nature and level of work required of this position.  They are not intended to be construed as an exhaustive list of all responsibilities and skills required of personnel so classified. Position available immediately. A two-year commitment is required.

 

APPLICATION: Please send application materials (cover letter, resume/CV) and a list of three professional references to carees@hmri.org. No phone calls, please.

Research Technician, Neurosciences Research
Posted 64 days ago
Post Date: August 3, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

START DATE: May/June 2022

DEPT: Neurosciences

SALARY LEVEL: $20-22 per hour (commensurate with experience)                                    

SUMMARY:

Huntington Medical Research Institutes is an independent, nonprofit organization dedicated to improving lives through patient-focused scientific research. Our brand-new state of the art laboratory anchors the biomedical corridor on South Fair Oaks in Pasadena. Our scientists' research focuses on the connection between the brain and heart, developing diagnostic tools to help treat common diseases of these vital organs that affect every family.

The Research Technician’s primary purpose is to prepare biological samples for biochemistry, identify molecules with methods including chromatography-mass spectrometry, and analyze the data. Some in-house training will be offered for the specific methods and equipment.

The Research Technician reports directly to Dr. Alfred Fonteh and interfaces with other HMRI staff members from the neurosciences department (research investigators, research scientists, and laboratory supervisors). 

JOB QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed below are representative of the knowledge, skill, and/or ability required. 

  • Carries out technical aspects of scientific studies.
  • May be involved with analysis of data, presentations, writing, lab management, etc.
  • The Research Technician also performs a wide range of job duties as assigned and requested.

 Education and Experience

  • A Bachelor’s degree in a scientific discipline with two years’ experience or MS degree with one year of experience or an equivalent combination of related education and experience.
  • Outstanding computer skills. Must be proficient with MS Office programs (Word, Excel, Outlook).
  • Experience in liquid chromatography and mass spectrometry.
  • Excellent written and oral communication skills.
  • Accurately maintain lab notebooks.
  • Keep records of lab inventories.
  • Sound judgement and decision-making capability.
  • Observes laboratory safety and security procedures.
  • Uses laboratory equipment and materials properly.
  • Must be reliable and conscientious self-starter with excellent attention to detail and the ability to coordinate multiple projects and deadlines.
  • Ability to build and maintain strong relationships with colleagues, building respect, consensus, and trust across reporting lines.
  • Follow instructions from supervisors and HMRI leadership.

SUPERVISORY RESPONSIBILITIES:

None.

PHYSICAL DEMANDS:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and speak or listen.  The employee frequently is required to use hands, fingers, and arms to operate personal computers, telephones, other business-related equipment, and work near moving mechanical parts.  The employee is occasionally required to stand and walk. The employee is occasionally exposed to low levels of airborne particles or toxic chemicals, bloodborne and airborne pathogens or infectious materials.

While performing the duties of this job, the noise level in the work environment is usually quiet to moderate and is below the EPA recommended noise levels.

The employee must occasionally lift and/or move more than 30 pounds.

Specific vision abilities required by this job include the following: Close vision; Distance vision; Color vision; Peripheral vision; Depth perception and ability to adjust focus.

The above statements are intended to describe the general nature and level of work required of this position.  They are not intended to be construed as an exhaustive list of all responsibilities and skills required of personnel so classified.

APPLICATION: Please send application materials (cover letter, resume/CV) and a list of three professional references to careers@hmri.org. No phone calls, please.

 

EEO POLICY:

HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

 

Neurovascular Postdoctoral Fellow
Posted 64 days ago
Post Date: August 3, 2022   Author: Human Resources
Job Type: Full Time
Location: Pasadena, CA

SALARY LEVEL: Salary is determined based on PhD receipt date according to a set salary schedule, which begins at $54,080.00 up to a maximum of $59,000.00 plus benefits.                       

A postdoctoral position is available immediately in the Neurovascular Research Program at Huntington Medical Research Institutes (HMRI), Pasadena, California, to investigate novel GABA signaling mechanisms during brain development. The project will examine the key fundamental mechanisms of action of vascular GABA signaling components during the postnatal period and how these differentially shapes blood flow and adult behavioral paradigms. We welcome applications from highly motivated and independent-minded individuals. Candidates must have a PhD degree in biology, with expertise in Neuroscience, Vascular Biology or Electrophysiology. Candidates with a good track record of publications, and experience in whole-cell patch clamp electrophysiology, mouse genetic models, and tamoxifen administration will be given priority. Experience in small animal handling and surgery is a prerequisite. The candidate must have effective communications skills and an aptitude for mentoring students. The initial appointment will be for two years with the possibility of extension. Salary will be commensurate with qualifications, laboratory experience, and institutional guidelines.

Huntington Medical Research Institutes is an independent, nonprofit organization dedicated to improving lives through basic and patient-focused scientific research. Our brand-new state of the art laboratory anchors the biomedical corridor on South Fair Oaks in Pasadena. This position offers outstanding scholarly and scientific opportunity in a collegial and collaborative department at HMRI, as well as other related departments at USC and Caltech.

TO APPLY: Please send application materials (CV, a brief summary of career goals and objectives) and a list of three professional references to careers@hmri.org. No phone calls, please.

 

Anju Vasudevan, PhD
Associate Professor and Scientific Director,
Neurovascular Research Program
Huntington Medical Research Institutes (HMRI)
Lab website: http://www.theabdl.org/

EEO POLICY: HMRI provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

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