2002 Publications

Cardiology

Bing RJ.  Past Truth and Present Poetry.  Dr.  Patterson and his missing gene.  Heart News and Views 10(1):1-2, 2002.

Bing RJ.  Past Truth and Present Poetry.  Science as business. Heart News and Views 10(3):1-2, 2002

Bing RJ.  Past Truth and Present Poetry.  Vital decisions-Committee or individuals?  Heart News and Views 10(3):1-2, 2002

Bing RJ.  Reply.  Journal of the American College of Cardiology 40:3, 2002.
 

Bing RJ, Lomnicka M.  Why do cyclo-oxygenase-2 inhibitors cause cardiovascular events?  Journal of the American College of Cardiology 39:3, 2002.

Miyataka M, Rich K, Ingram M, Yamamoto T, Bing RJ.  Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.  Hypertension 39:785-789, 2002.

Gene Therapy

Baltayan A, Naritoku WY, Chaiwun B, Tsao-Wei DD, Groshen S, Hern RA, Gusterson BA, Taylor CR, Imam SA.  LEA.135 expression: Identifies low-risk patients with breast ductal carcinoma in situ.  Anticancer Research 22:2933-2938, 2002.

Liver

Goodman Z, Marcellin P, Chang TT, Lim SG, Tong M, et al.  48 weeks of adefovir dipivoxil (ADV) results in improvement in fibrosis and decreases progression of fibrosis in a double-blind, randomized, placebo-controlled study for the treatment of patients with HbeAg+ chronic hepatitis B.  Hepatology 36(4):(841)373A, 2002.

Heathcote J. Chang TT, Lim SG, Hadziyannis S, Tassopoulos N, Tong M, et al.  Safety profile of 48 weeks of adefovir dipivoxil (ADV) 10 mg for the treatment of chronic hepatitis B: An integrated analysis of two phase III studies.  Hepatology 36(4): (1882) 633A, 2002.

Lai CL, Leung N, Teo EK, Tong M, Wong F, Hann HW, et al.  International multicenter traila of LDT (Telbivudine), alone and in combination with lamivudine, for chronic hepatitis B: An interim analysis.  Hepatology, 36(4):(554)301A, 2002.

Marcellin P, Chang TT, Hadziyannis S, Tong M, et al.  Adefovir dipivoxil (ADV) 10 mg: Results in consistent histological improvement in HbeAg+ and HbeAg- patients regardless of baseline demographic or disease characteristics.  Hepatology, 36(4):(1869)630A, 2002.

Marcellin P, Chang TT, Lim SG,  Sievert W. Tong M, Jain A.  Adefovir dipivoxil (ADV) 10 mg for the treatment of patients with HbeAg+ chronic hepatitis B: Continued efficacy beyond 48 weeks.  Hepatology 36(4): (840)373A, 2002.

Patel K, Tong M, Pockros PJ, McHutchinson JG, Blatt LM.  Baseline serum alanin aminotransferase as a predictor of virologic response to interferon therapy in chronic hepatitis C patients.  Hepatology 36(4): (1743)599A, 2002.

Seo S, Tong M, Blatt L. Conrad A.  Diagnosis and treatment of autoimmune hepatitis in a community hospital setting.  Hepatology 36(4): (1367)505A, 2002.

Tong M, Blatt L, Kao V.  The clinical course of 481 patient with chronic hepatitisÝB.  Hepatology, 36(4): (1808)614A, 2002.

Tong M, Schiff E, Jenson DM, et al.  Preliminary analysis of a phase II study of heptazyme: A nuclease resistant ribozyme targeting hepatitis C virus (HCV) RNA,  Hepatology 36(4):(788)360A, 2002.

Lung

Glovsky MM, Taylor PE, Valenta R and Flagan RC.  Pollen fragments that may trigger asthma are released directly from major allergenic plants.  FASEB (Federation of American Societies for Experimental Biology) 16:A673, 2002.

Taylor PE, Flagan R, Glovsky MM.  Pollen fragments are released as respirable aerosols from major allergenic trees and weeds.  Journal of Allergy and Clinical Immunology 109:S303, 2002.

Taylor PE, Flagan RC, Valenta R, Glovsky MM.  Release of allergens in respirable aerosols: a link between grass pollen and asthma.  Journal of Allergy Clinical Immunology 109:51-56, 2002.

Magnetoencephalography

Akhtari M, Bryant H, Mamelak A, Heller L, Shih JJ,  Mandelkern M, Matlachov A, Ranken DM, Best E, DiMauro MA, Lee R, Sutherling WW.  Conductivities of three-layer live human skull.  Brain Topography 14(3):151-167, 2002.

Akhtari M, Bryant H, Flynn E, Lopez NP, Padilla R, Merrifield W. Mamelak AN, Sutherling WW.  Comparison of BEM with 3-shell sphere model using actual skull conductivity.  Abstract.  American Epilepsy Society 56th Annual Meeting, Seattle, Dec. 2002.

Akhtari M, Bryant H, Flynn E, Lopez NP, Padilla R, Merrifield W, Mamelak AN, Sutherling WW.  MEG, EEG source localization and conductivities of the live human skull.  Presented at the 13th International Conference on Biomagnetism BioMag, 2002, Jena, Germany, August 10-14, 2002.

Akhtari M, Mamelak AN, Lopez NP, Padilla R, Merrifield W, Sutherling WW.  Unique localization information of MEG in neocortical epilepsy and tumors in four neurosurgical patients.  Presented at the 13th International  Conference on Biomagnetism, BioMag, Jena, Germany, August 10-14, 2002.
 
Lopez NP, Akhtari M, Mamelak AN, Merrifield W. Sutherling WW.  Magneto-oculogram from magnetic cosmetics.  Presented at the 13th International Conference on Biomagnetism, BioMag, Jena, Germany, Aug. 10-14, 2002.

Mamelak AN, Lopez NP, Akhtari M, Sutherling WW.  Magnetoencephalography-directed surgery in patients with neocortical epilepsy.  Journal of Neurosurgery 97, 865-873, 2002.

Merrifield WS, Thyerlei D, Lopez NP, Akhtari M, Mamelak AN, Riggs ML, Sutherling WW.  MEG spike dipole clusters have different statistics in different epilepsies. Epilepsia 43(S7):315, 2002.

Ossadtchi A, Baillet S, Mosher JC, Thyerlei D, Lopez NP, Sutherling WW, Leahy R.  Automated spike detection and source localization in MEG using independent component analysis (ICA) and spatial-temporal clustering.  Submitted to Clinical Neurophysiology, 2002.

Thyerlei D, Akhtari M, Bryant HC, Mamelak AN, Merrifield WS, Sutherling WW.  Comparison of boundary element model (BEM) the three-spherical shell model using actual skull conductivities.  Epilepsia 43(S7):37, 2002.

Thyerlei D, Lopez NP, Padilla RD, Maleeva T, Mamelak AN, Merrifield WS, Akhtari M, Sutherling WW.  Presurgical epileptic focus detection, an interesting case: ictal single photon emission computer tomography (SPECT) and grid localizations differ from interictal neuromagnetometer (MEG) and depth electrode localizations.  C148, ACNS, New Orleans, 2002.

MR Spectroscopy

Bluml S, Moreno-Torres A, Shic F, Nguy C-H, Ross BD. Tricarboxylic acid cycle of glia in the in vivo human brain. NMR in Biomedicine 15:1-5, 2002.

Cecil KM, Lin AP, Ross BD, Egelhoff JC.  Methylsulfonylmethane observed by in vivo proton magnetic resonance spectroscopy in a 5-year-old child with developmental disorder: Effects of dietary supplementation. Journal of Computer Assisted Tomography. September 26(5):818-20, 2002.

Kanamori K, Ross BD, Kondrat RW.  Glial uptake of neurotransmitter glutamate from the extracellular fluid studied in vivo by microdialysis and (13)C NMR. Journal of Neurochemistry 83(3):682-95, 2002.

Kondrat RW, Kanamori K, Ross BD.  In vivo microdialysis and gas-chromatography/mass-spectrometry for 13C-enrichment measurement of extracellular glutamate in rat brain. Journal of Neuroscience Methods
120:179-92, 2002.

Abstracts

Bluml S, Shic F, Lai L, Yahya K, Lin AP, Ross BD.  Glutamate-glutamine cycling in epileptic patients on ketogenic diets.  Proceedings 10th, International Society of Magnetic Resonance in Medicine, 2002.

Ross BD, Bluml S, Seymour KJ, Tan J, Hwang JH, Lin A.  Systemically induced encephalopathies:  Newer clinical applications of MRS.  MR of Head, Neck, and Spine, No. 1116, 2002.

Shic F, Ross BD, Yahya K, Lin AP, Lai L, Bluml S.  A protocol for the synchronous assay of in vivo glial and neuronal metabolic rates in man.  Proceedings 10th, International Society of Magnetic Resonance in Medicine, 2002.

Invited Lectures

International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii
Brian Ross, MD, PhD, D Phil. (Oxon).  Dynamic Metabolic Analysis at Huntington Medical Research Institutes, Pasadena: What works and what does not-and why it is better than isotopomer analysis. 10th International Society for Magnetic Resonance in Medicine, 2002.

Alzheimer's Association, Stockholm, Sweden
Lin AP, Shic F, Zapata M, Pang W, Ross BD.  Magnetic resonance spectroscopy diagnosis of Alzheimer disease: Verification at autopsy. 8th International Conference on Alzheimer's disease and related disorders, 2002.

Lai L, Shic F, Lin A, Shilyansky E, Ross BD.  Earlier detection of Alzheimer's disease by short TE 1H Magnetic resonance spectroscopy in the hippocampus. 8th International Conference on Alzheimer's disease and related disorders, 2002.

Shic F, Lai L, Lin A, Yahya K, Moreno A, Bluml S, Ross BD.  13 C glucose magnetic resonance spectroscopy of human neurodegenerative disorders. 8th International Conference on Alzheimer's disease and related disorders, 2002.

Alex P. Lin, Shic F, Enriquez C, Ross BD.  Evidence of reduced glutamate neurotransmission in patients with Alzheimer's disease-An in vivo 13C study.
19th European Society for Magnetic Resonance in Medicine and Biology, 2002.

Courses

Alex Lin, Mary Munoz and Brian Ross.  15th Clinical MR Spectroscopy Training Course.  Huntington Medical Research Institutes. Pasadena, June, 2002.

Molecular Neurology

Fonteh AN, Cowan R, Harrington MG.  Importance of proteins that metabolize polyunsaturated fatty acids in the pathogenesis of Alzheimer's disease. 5th Siena Conference on Functional Proteomics,
p. 91, 2002.

Fonteh AN, Cowan R, Harrington MG.  Ictal and interictal changes in proteins that metabolize polyunsaturated fatty acids in cerebrospinal luids of migraineurs and control subjects. 5Th Siena Conference on Functional Proteomics, p. 259, 2002.

Harrington MG, Cowan R, Fonteh AN. Discovering fundamental processes in migraine by analyzing dynamic changes in cerebrospinal fluid composition throughout fluctuating clinical states. 5th Siena Conference on Functional Proteomics, p89, 2002.

Harrington MG, Biringer R, Huehmer A, Bondarenko P, Amato H, Hancock W, Lardine IJ, Dalleska N, Cowan R, Fonteh AN.  Methods for the study of cerebrospinal fluid composition. 5Th Siena Conference on Functional Proteomics, p 240, 2002.
 
Fonteh AN. Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils: Evidence of different arachidonate pools. European Journal of Biochemistry 269, 3760-3770, 2002.

Molecular Oncology and Genetics

Huang T-T, Raineri I, Eggerding FA, Epstein CJ.  Transgenic and mutant mice for oxygen free radical studies.  Methods in Enzymology 349:191-213, 2002.

Neural Engineering

Agnew WF, McCreery DB.  Principles of safe and effective nerve stimulation.  In: New Perspectives in Sacral Nerve Stimulation. U. Jonas and V Grunewald, eds. (London, Martin Dunitz), pp. 29-42, 2002.

Liu NQ, Lossinsky AS, Popik W, Li X, Gujuluva C, Kriederman B, Roberts J, Pushkarsky T, Bukrinsky M, Witte M, Weinand M, Fiala M.  Human immunodeficiency virus type-1 enters brain microvascular endothelia by micropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway.  Journal of Virology 76(10), 6689-6700, 2002.

Lossinsky AS, McCreery DB, Bullara LA, Pikov V, Agnew WF.  Immunohistochemical and histochemical examination of neuronal changes after electrical stimulation of the feline sacral spinal cord.  Presented at the Society for Neuroscience 28, Nov.Ý5, in Orlando, FL, poster #505.7, 2002.

Mannoonkitiwongsa PS, Lossinsky AS, Pikov V, Liu X, Chavez J, Graham C, McCreery DB, Bullara LA, Agnew WF.  Comparison of Fluoro-Jade B, NeuN and cresyl violet as markers of degenerating cat cortical neurons following electrical stimulation.  NIH Neural Prosthesis, Bethesda, MD, 2002.

Mannoonkitiwongsa PS, Schultz RL.  Proper nomenclature of formaldehyde and paraformaldehyde fixatives for histochemistry. The Histochemical Journal 34:365-367, 2002.

McCreery DB, Agnew WF, Bullara LA.  The effects of prolonged intracortical microstimulation on the excitability of pyramidal tract neurons in the cat.  Annuals of Biomedical Engineering 30, 107-119, 2002.

Pikov V, Wrathall JR.  Altered glutamate receptor function during recovery of bladder detrusor-external urethral sphincter coordination in a rat model of spinal cord injury.  Journal of Pharmacology & Experimental Therapeutics 300, 421-427, 2002.

Prostate

Jones LW.  Prostate Cancer Mitochondria, presented at the Western Urologic Forum 50th Anniversary meeting, March 2002.